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National Diabetes Audit 2021-22, Young People with Type 2 Diabetes - Overview

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National Diabetes Audit 2021-22, Young People with Type 2 Diabetes - Overview


Young Type 2 Dashboard is now available

The NDA Young People with Type 2 Dashboard is now available. The latest data is available here:  National Diabetes Audit dashboards.

11 October 2024 09:00 AM

Changes to NDA reporting

NHS England are currently reviewing the routine production of NDA State of the Nation reports. Please note that data will still be released via dashboards and standalone data files whilst this review is being conducted.

To help inform this review we would be grateful if users can provide feedback on their use of the State of the Nation reports using the feedback survey available in the ‘Related links' section of this page.

3 June 2014 00:00 AM

Summary

The National Diabetes Audit (NDA) and the National Paediatric Diabetes Audit (NPDA) provide a comprehensive view of diabetes care in England and Wales. They measure the effectiveness of diabetes healthcare against National Institute for Health and Care Excellence (NICE) Clinical Guidelines and NICE Quality Standards.

This is the second Young People with Type 2 Diabetes report (1). It aims to document the number of people with type 2 diabetes up to the age of 40 years, their patient characteristics and the diabetes care they receive. This is important because adverse diabetes and cardiovascular outcomes are more common in people who develop type 2 diabetes at an earlier age and it is thought the numbers of affected individuals are increasing (2,3).


Highlights

This State of the Nation overview details the findings and recommendations relating to diabetes care for young people (4) with type 2 diabetes for the 2021-22 audit (5).

The detailed analyses behind this summary report can be found here: NDA 2021-22, Young People with Type 2 Diabetes - Detailed Analysis Report

The State of the Nation overview and detailed analysis report cover:

  • Trends in cross-sectional prevalence and characteristics of young people with type 2 diabetes over the last 5 audit years (2017-18 to 2021-22)
  • Receipt of care processes and treatment target achievement in people with type 2 diabetes at young age
  • Treatment received, including statins and antihypertensive treatment, along with the location of care.

Notes:

1. The first Young People with Type 2 Diabetes report can be accessed here: Young People with Type 2 Diabetes, 2019-20.

2. TODAY Study Group. Long-Term Complications in Youth-Onset Type 2 Diabetes, The New England Journal of Medicine 2021; 385:416-26 

3. Sattar and others. Age at Diagnosis of Type 2 Diabetes Mellitus and Associations With Cardiovascular and Mortality Risks, Circulation 2019; 139(19):2228-2237

4. Young people are defined as those up to the age of 40 years.

5. 2021-22 audit covers the period 01 January 2021 to 31 March 2022.


Cohort

NDA (people of all ages) data was linked to NPDA (young people attending specialist paediatric diabetes clinics) data to create a cohort of young people with type 2 diabetes from both data sets. Where necessary, to confirm the diagnosis and type of diagnosis, HbA1c and prescription (1) information were used.  

Due to the diagnosis validation steps used in this report, the cohort of young people with type 2 diabetes used in this report differs from that used in NDA Core Report 1 2021-22 (2,3).

For this report the cohort was split into the following age groups (4):

  • ‘Under 12 years’, ’12 to 15 years’ and ’16 to 18 years’ to capture the variable clinical presentations amongst pre-pubertal children.
  • ’19 to 25 years’ and ’26 to 39 years’ to reflect the early stages of adulthood.

For certain analyses, these age groups were compared to ‘40 to 59 years’ and ‘60 to 79 years’ age groups to understand trends across all ages (4).

Notes:

1. Prescription data for Semaglutide (GLP-1 receptor agonist), Ertugliflozin (SGLT2 inhibitor), Empagliflozin with linagliptin (SGLT2 inhibitor with DPP-4 inhibitor), and Saxagliptin with dapagliflozin (DPP-4 inhibitor with SGLT2 inhibitor) has not been included within the NDA drugs data collection. Therefore these drugs have not been included in the cohort for this report.  This means that individuals may have been omitted from the cohort when they should have been included.  Work is ongoing to ensure all glucose-lowering medication are collected and included in future publications.

2. The NDA Core Report 1 2021-22 uses the diagnosis type in NDA whereas in this report, a series of diagnosis validation steps are used to decide the cohort of young people with type 2 diabetes. See Methodology in the accompanying detailed report for details of this process.

3. Both reports cover the period 01 January 2021 to 31 March 2022.

4. These age groups align with those used for the first Young People with Type 2 Diabetes report: Young People with Type 2 Diabetes, 2019-20.

Young People with Type 2 Diabetes dashboard

Through this dashboard, you can explore local analysis on characteristics, treatment target achievement and treatment.


Key findings and recommendations

Key finding 1: Characteristics and trends

  • There were 139,255 people under the age of 40 with type 2 diabetes in 2021-22, accounting for 4.8% of all type 2 diabetes cases under the age of 80 in England and Wales (see Table 1). Between 2017-18 and 2021-22, there was a steady year-on-year increase in the number of people with type 2 diabetes across all age groups, with a total percentage increase of 11.6% from 2017-18 to 2021-22. However, a steeper rise was observed in those under the age of 40 with a percentage increase of 18.7% between 2017-18 and 2021-2022 compared to 11.3% in those aged between 40 and 79 years old.

Table 1: Number of people with type 2 diabetes, by age group and audit year, England and Wales, 2017-18 to 2021-22

  Audit year
Age group 2017-18 2018-19 2019-20 2020-21 2021-22
Under 40 117,270 123,830 129,200 132,000 139,255
40 - 79 2,488,330 2,577,295 2,674,395 2,705,585 2,769,415
Total 2,605,600 2,701,130 2,803,595 2,837,585 2,908,670
  • A greater proportion of people aged 19-25 years with type 2 diabetes were female (for example 61.3% were female in 2021-22) with equal proportions of males and females in those aged 26-39 years old (for example 50.8% were female in 2021-22). However, males predominated in older age groups (for example. in 2021-22, 58.4% of 40-59 year olds and 57.3% of 60-79 years old were male).
  • Young people (aged under 40 years old) with type 2 diabetes were more likely to be from Asian and mixed ethnic groups compared to older people with type 2 diabetes (in 2021-22, 29.6% of 26-39 year olds were from Asian ethnic groups and 2.1% were from mixed ethnic groups compared to 20.9% and 1.7% of 40-59 year olds respectively; see Figure 1). When compared to the national England and Wales picture (1), people from Asian and black ethnic groups were over-represented in younger age groups of people with type 2 diabetes (in 2021-22 (2), 32.0% of 26-39 year olds with type 2 diabetes were from Asian ethnic groups and 7.4% were from black ethnic groups, compared to 11.9% and 4.3% of the national total in this age group respectively; see Figure 2).

Percentage of people with type 2 diabetes by age group and ethnicity England and Wales 2017 - 2018 to 2021 - 2022

Percentage of people with type 2 diabetes by age group and ethnicity compared to those in equivalent age groups in the general population England and Wales 2021 - 2022

  • Young people (aged under 40 years old) with type 2 diabetes were more likely to be from deprived areas compared to older people with type 2 diabetes (in 2021-22, 34.4% of people with type 2 diabetes aged 19-25 years old and 34.3% of those aged 26-39 years old lived in the most deprived areas compared to 29.3% and 22.3% of those aged 40-59 and 60-79 years old respectively).
  • People with type 2 diabetes aged 19-25 and 26-39 were more likely to be living with obesity, accounting for 77.3% and 74.6% respectively in 2021-22. The proportion of people with type 2 diabetes living with obesity increased over the 5-year period; the proportions in those aged 19-25 and 26-39 rose from 73.4% and 71.7% in 2017-18 to 77.3% and 74.6% in 2021-22 respectively (see Figure 3).

Percentage of people with type 2 diabetes by age group and BMI England and Wales 2017 - 2018 to 2021 - 2022

  • People with type 2 diabetes under the age of 16 were most likely to be seen by specialist diabetes services in secondary care (89.3% of under 12 year olds and 91.6% of 12-15 year olds). As age increased, young people with type 2 diabetes were more likely to be exclusively under the care of their general practice (GP); 70.1% of those aged 16-18 years old attended specialist secondary care, falling to 30.6% of 19-25 year olds.

See Characteristics and trends of the detailed report for further information.

Notes:

1. National England and Wales population figures based on Census 2021 data. For more information see https://census.gov.uk/.

2. People whose ethnicity was ‘Not stated/Not known’ were excluded from these calculations.

3. People whose BMI category was unknown were excluded from these calculations. How BMI categories have been assigned differ between children (up to 18 years old) and adults. In adults, categories are assigned on BMI ranges and ethnicity group. For children, their BMI is compared to reference values for children of the same sex and similar age that took part in national surveys. See 'Care processes' under definitions in Additional information for further details.

4. Totals may not sum due to disclosure control. See Additional information for more details.

Recommendation 1

To help reduce the number of young people with type 2 diabetes and their associated inequalities, commissioners of care should optimise access to and uptake of the national type 2 diabetes programmes designed to prevent onset (NHS Diabetes Prevention Programme) and support remission (NHS Type 2 diabetes path to remission) in everyone age 18+ and in all societal groups.

Key finding 2: Care Processes and Treatment Targets

  • People aged 19 to 39 years old with type 2 diabetes were less likely to receive all, 8 care processes (1) (26.5% of 19-25 year olds and 34.7% of 26-39 year olds) compared to older people with type 2 diabetes (44.0% and 51.6% of 40-59 and 60-79 year olds respectively; see Figure 4).

Percentage of people with type 2 diabetes who compared all 8 diabetes care processes by age group England and Wales 2021 - 2022

  • The proportion of people with type 2 diabetes achieving the blood pressure treatment target steadily decreased with age from 67.8% of 12-15 year olds to 58.4% of 26-39 year olds; after which the proportion achieving the treatment target increased with age up to 70.1% of 60-79 year olds.
  • Fewer than one-third (28.6%) of people with type 2 diabetes aged 19-25 years old achieved the secondary prevention statin treatment target (2). 
  • In people under 40 years old with type 2 diabetes, characteristics most associated with achieving an HbA1c ≤ 58 mmol/mol included being female (odds ratio (OR) is 1.44 when compared to male), being from ethnic groups other than white (for example OR for Asian ethnic groups is 1.23 and OR for black ethnic groups is 1.17 when compared to white ethnic groups), and having a shorter diabetes duration (OR for 2-9 years is 0.60 when compared to duration of less than 2 years) (3). This is supported by additional analysis (4) looking at people under 40 years old with type 2 diabetes, which shows 56.7% of females compared to 49.3% of males, 56.3% of people from Asian ethnic groups and 55.0% of people from black ethnic groups compared to 51.2% of people from white ethnic groups, and 62.8% of people with a diabetes duration of less than 2 years compared to 50.8% of people with a diabetes duration of 2-9 years achieved an HbA1c ≤ 58 mmol/mol.
  • In people under 40 years old with type 2 diabetes, characteristics associated with a reduced likelihood of achieving an HbA1c ≤ 58 mmol/mol included being from a more deprived area (most deprived OR is 0.80 when compared to least deprived) and having a longer diabetes duration (OR for 10 years and over is 0.31 when compared to duration of less than 2 years) (3). This is supported by additional analysis (4) looking at people under 40 years old with type 2 diabetes, which shows 51.7% of people from a most deprived area compared to 56.7% of people being from a least deprived area, and 35.2% of people with a diabetes duration of 10 years and over compared to 62.8% of people with a diabetes duration of less than 2 years achieved an HbA1c ≤ 58 mmol/mol.
  • In people under 40 years old with type 2 diabetes, having an HbA1c > 86 mmol/mol was associated with black ethnic groups (OR is 1.23 when compared to white ethnic groups), deprivation (most deprived OR is 1.33 when compared to least deprived), longer diabetes duration (OR for 10 years and over is 2.36 when compared to duration of less than 2 years), and lower BMI categories (OR for underweight category is 1.50 when compared to healthy weight category) (3). This is supported by additional analysis (4) looking at people under 40 years old with type 2 diabetes, which shows 20.4% of people from black ethnic groups compared to 17.2% of people from white ethnic groups, 17.7% of people from a most deprived area compared to 14.1% of people being from a least deprived area, 24.7% of people with a diabetes duration of 10 years and over compared to 12.5% of people with a diabetes duration of less than 2 years, and 26.4% of people in the underweight BMI category compared to 19.2% of people in the healthy weight BMI category had an HbA1c > 86 mmol/mol.

See Care processes and treatment targets of the detailed report for further information.

Notes:

1. Diabetes Eye Screening (eye exam/retinopathy) data is not collected for Wales. Therefore, this report is restricted to 8 of the 9 care processes for England and Wales.

1. Care processes assessed based on age:

  • Under 12s: HbA1c, BMI, cholesterol, blood pressure and albumin
  • 12-18 years: HbA1c, BMI, cholesterol, blood pressure, albumin and foot exam
  • 19 years and over: HbA1c, BMI, cholesterol, blood pressure, albumin, foot check, smoking status and creatinine

For example, a person aged 10 would be assessed for the HbA1c, BMI, cholesterol, blood pressure and albumin care processes, but not the foot exam, smoking status and creatinine care processes. Therefore if they received the HbA1c, BMI, cholesterol, blood pressure and albumin care processes then in this analysis they are recorded as having received 'all 8 care processes'.

2. This analysis relates to all people in the cohort, not just people with CVD.

3. Analysis of characteristics associated with HbA1c levels and their respective odds ratios have been derived from logistic regression models. Full analysis from these models can be found in the Care processes and treatment targets page of the detailed report. For information on logistic regression models and odds ratios see Additional information. As the predictive ability of the models are weak (c statistic around 0.6), the findings from these models should be considered in conjunction with the additional analysis in the Open data file accompanying the detailed report.

4. Analysis can be found in the Open data file accompanying the detailed report.

5. For more details on each of the care processes see Additional information.

6. Totals may not sum due to disclosure control. See Additional information for more details.

Recommendation 2

Commissioners of care should work with primary and secondary care diabetes services to reduce age, ethnicity and deprivation related inequalities in completion of NICE recommended care processes.

Key finding 3: Antihypertensive treatment

  • People with type 2 diabetes aged 19-25 and 26-39 years old were less likely to be prescribed antihypertensive treatment (for example 15.6% and 27.0% of females respectively) than older people (for example in females 56.2% of 40-59 year olds and 78.4% of 60-79 year olds). Although hypertension is less common at younger ages, it is notable that blood pressure treatment targets are less often achieved in under 40 year olds as a whole when compared to older age groups. Around a quarter of females aged 19-39 years old that might be planning pregnancy were prescribed antihypertensive treatment (26.0%; see Figure 5).

percentage of people with type 2 diabetes by age group prescription of antihypertension treatment and sex England and Wales 2021 - 2022

See Antihypertensive treatment and statins of the detailed report for further information.

Notes:

1. Totals may not sum due to disclosure control. See Additional information for more details.

Recommendation 3

Commissioners of care for young people with type 2 diabetes should work with healthcare providers to: 

- reduce variation in both NICE recommended glucose and blood pressure control

- achieve cardiovascular risk reduction

- reduce adverse foetal and maternal pregnancy outcomes



Last edited: 11 October 2024 9:04 am


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