Skin - Pathology

This is the site specific section for additional skin cancer specific data items to be recorded. These will be aligned within the schema to form a single report. Data items within the following groups have been re-ordered to improve data collection and prevent errors, in some cases the same data item may be collected within more than one section.

This is a new section for v4 and allows for only Basal Cell Carcinoma (BCC) data to be recorded.

May be one occurrence per pathology report (0..1)

Note: the following data items has been retired from v4.0:

• Deep Invasion Indicator for PT3
• Deep Invasion Indicator for PT4

Skin Cancer Lesion Indicator

This is the specimen number or letter used to identify the specimen within a report. Where more than one primary skin cancer is reported on the same pathology report, record the lesion number or letter as specified on the pathology report.

Perineural Invasion

Is there perineural invasion (invasion into perineurium of nerve bundles – PNI).

Lesion Diameter Greater Than 20mm Indicator

Is the diameter of the lesion greater than 20mm?

This is a new section for v4 and allows for only Squamous Cell Carcinoma (SCC) data to be recorded.

May be one occurrence per pathology report (0..1)

Skin Cancer Lesion Indicator

This is the specimen number or letter used to identify the specimen within a report. Where more than one primary skin cancer is reported on the same pathology report, record the lesion number or letter as specified on the pathology report.

Perineural Invasion

Is there perineural invasion (invasion into perineurium of nerve bundles – PNI).

Lesion Diameter Greater Than 20mm Indicator

Is the diameter of the lesion greater than 20mm?

Clarks Level IV Indicator

Greater than or equal to Clarks level IV.

Notes:

• ‘Clark level IV Indicator’ is only required to differentiate between T1a and T1b melanomas when mitotic rate cannot be measured AND in the absence of ulceration
• in these cases, ‘Clarks level lV’ or above categorises the melanoma as stage T1b

Lesion Vertical Thickness Greater Than 2mm Indicator

Is the vertical thickness of the lesion greater than 2mm?

This section allows for only Malignant Melanoma (MM) data to be recorded.

May be one occurrence per pathology report (0..1)

Skin Cancer Lesion Indicator

This is the specimen number or letter used to identify the specimen within a report. Where more than one primary skin cancer is reported on the same pathology report, record the lesion number or letter as specified on the pathology report.

Ulceration Indicator

Loss of full thickness of epidermis associated with reactive changes (ulceration).

Mitotic Rate (Skin)

Mitotic rate per square millimetres (mm).

Note:

• May also be known as Mitotic Index or Count

Microsatellite Or In-Transit Metastasis Indicator

Is there evidence of Microsatellite or in transit metastases?

Tumour Regression Indicator

Area of loss of tumour associated with reactive changes?

Breslow Thickness

Breslow thickness in mm, can be recorded to nearest 0.01mm where clinically appropriate.

Note:

• Breslow thickness should be measured to a minimum of one decimal place but at times to a greater degree of precision as to allow accurate

Tumour Infiltrating Lymphocytes (TILS)

Type of TILS. Tumour infiltrating lymphocytes (TILS) are white blood cells that have left the bloodstream and migrated into a tumour.

Sentinel Nodes Examined Number

Number of sentinel nodes sampled.

Sentinel Nodes Positive Number

Number of sentinel nodes positive.

Post SNB Completion Lymphadenectomy – Nodes Sampled Number

Post SNB completion lymphadenectomy, number of nodes sampled. This procedure is not carried out in all cases.

Post SNB Completion Lymphadenectomy – Nodes Positive Number

Post SNB completion lymphadenectomy, number of nodes positive. This procedure is not carried out in all cases.