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Part of Cancer staging guidance sheets

Carcinoma of skin (excluding eyelid, head and neck, perianal, vulva and penis) (ICD10 C44.5-7, C63.2)

Current Chapter

Current chapter – Carcinoma of skin (excluding eyelid, head and neck, perianal, vulva and penis) (ICD10 C44.5-7, C63.2)


Introduction

This is the data sheet for TNM 8th edition staging of the carcinoma of skin (excluding eyelid, head and neck, perianal, vulva and penis) (ICD10 C44.5-7, C63.2)

For more detailed information regarding TNM staging, please see pages 133-135 of the UICC TNM 8 book or visit the Wiley and UICC website.


Stage groupings

Stage Group

T stage

N stage

M stage

Stage 0

Tis

N0

M0

Stage I

T1

N0

M0

Stage II

T2

N0

M0

Stage III

T3

N0

M0

 

T1, T2, T3

N1

M0

Stage IVA

T1, T2, T3

N2, N3

M0

 

T4

Any N

M0

Stage IVB

Any T

Any N

M1


TNM clinical classification

T - primary tumour

T value Description

TX

Primary tumour cannot be identified

T0

No evidence of primary tumour

Tis

Carcinoma in situ

T1

Tumour 2 cm or less in greatest dimension

T2

Tumour >2 cm and ≤4 cm in greatest dimension

T3

Tumour >4 cm in greatest dimension or minor bone erosion or perineural invasion or deep invasion*

T4a

Tumour with gross cortical bone/marrow invasion

T4b

Tumour with axial skeleton invasion including foraminal involvement and/or vertebral foramen involvement to the epidural space

Note:

* Deep invasion is defined as invasion beyond the subcutaneous fat or >6 mm (as measured from the granular layer of adjacent normal epidermis to the base of the tumour); perineural invasion for T3 classification is defined as clinical or radiographic involvement of named nerves without foramen or skull base invasion or transgression.

In the case of multiple simultaneous tumours, the tumour with the highest T category is classified and the number of separate tumours is indicated in parentheses, e.g., T2(5).

N - regional lymph nodes

N value Description

NX

Regional lymph nodes cannot be assessed

N0

No regional lymph node metastasis

N1

Metastasis in a single lymph node 3 cm or less in greatest dimension

N2

Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension or in multiple ipsilateral nodes none more than 6 cm in greatest dimension

N3

Metastasis in a lymph node more than 6 cm in greatest dimension

M - distant metastasis

M value Description

M0

No distant metastasis

M1

Distant Metastasis

Note:

* Contralateral nodes in non‐melanoma non‐head and neck cancer are distant metastases.


TNM pathological classification

pT - primary tumour

The pT and pN categories correspond to the T and N categories

pN - regional lymph nodes

pN value Description

pN0

Histological examination of a regional lymphadenectomy specimen will ordinarily include 6 or more lymph nodes. If the lymph nodes are negative, but the number ordinarily examined is not met, classify as pN0.


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Last edited: 21 December 2022 5:05 pm

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