Part of Cancer staging guidance sheets
Malignant melanoma of conjuctiva (ICD10 C69.0)
Introduction
This is the data sheet for TNM 8th edition staging of malignant melanoma of conjuctiva (ICD10 C69.0).
For more detailed information regarding TNM staging, please see pages 218-220 of the UICC TNM 8 book or visit the Wiley and UICC website.
TNM clinical classification
T - primary tumour
| T value | Description |
|---|---|
|
TX |
Primary tumour cannot be assessed |
|
T0 |
No evidence of primary tumour |
|
Tis |
Melanoma confined to the conjunctival epithelium (in situ) a |
|
T1 |
Melanoma of the bulbar conjunctiva T1a - Tumour involves less than or equal to one quadrant b T1b - Tumour involves more than one but less than or equal to two quadrants T1c - Tumour involves more than two but less than or equal to three quadrants T1d - Tumour involves more than three quadrants |
|
T2 |
Malignant conjunctival melanoma of the non‐bulbar conjunctiva involving palpebral, forniceal, and/or caruncular conjunctiva T2a - Non‐caruncular tumour involves less than or equal to one quadrant T2b - Non‐caruncular tumour involves more than one quadrant T2c - Caruncular tumour involves less than or equal to one quadrant of conjunctiva T2d - Caruncular tumour involves more than one quadrant of conjunctiva |
|
T3 |
Tumour with local invasion into: T3a - Globe T3b - Eyelid T3c - Orbit T3d - Paranasal sinus, nasolacrimal duct, and/or lacrimal gland |
|
T3 |
Tumour invades perivesical tissue: T3a – microscopically T3b - macroscopically (extravesical mass) |
|
T4 |
Tumour invades central nervous system |
Note:
a - Melanoma in situ (includes the term primary acquired melanosis) with atypia replacing greater than 75% of the normal epithelial thickness with cytological features of epithelial cells, including abundant cytoplasm, vesicular nuclei, or prominent nucleoli, and/or presence of intraepithelial nest of atypical cells.
b - Quadrants are defined by clock hour, starting at the limbus (e.g., 6, 9, 12, 3) extending from the central cornea, to and beyond the eyelid margins. This will bisect the caruncle.
N - regional lymph nodes
| N value | Description |
|---|---|
|
NX |
Regional lymph nodes cannot be assessed |
|
N0 |
No regional lymph node metastasis |
|
N1 |
Regional lymph node metastasis |
M - distant metastasis
| M value | Description |
|---|---|
|
M0 |
No distant metastasis |
|
M1 |
Distant Metastasis |
TNM pathological classification
pT - primary tumour
The pT categories correspond to the T categories as per above.
| pT value | Description |
|---|---|
|
pTX |
Primary tumour cannot be assessed |
|
pT0 |
No evidence of primary tumour |
|
pTis |
Melanoma confined to the conjunctival epithelium (in situ)* |
|
pT1 |
Melanoma of the bulbar conjunctiva pT1a - Tumour 2.0 mm or less in thickness with invasion of the substantia propria pT1b - Tumour more than 2.0 mm in thickness with invasion of the substantia propria |
|
pT2 |
Melanoma of the palpebral, forniceal or caruncular conjunctiva pT2a - Tumour 2.0 mm or less in thickness with invasion of the substantia propria pT2b - Tumour more than 2.0 mm in thickness with invasion of the substantia propria |
|
pT3 |
Melanoma invades the eye, eyelid, nasolacrimal system or orbit pT3a - Invades the globe pT3b - Invade the eyelid pT3c - Invades the orbit pT3d - Invades the paranasal sinus and/or nasolacrimal duct or lacrimal sac |
|
pT4 |
Melanoma invades central nervous system |
Note:
* pTis Melanoma in situ (includes the term primary acquired melanosis) with atypia replacing greater than 75 % of the normal epithelial thickness, with cytological features of epithelioid cells, including abundant cytoplasm, vesicular nuclei or prominent nucleoli, and/or presence of intraepithelial nests of atypical cells.
pN - regional lymph nodes
The pN categories correspond to the N categories.
Last edited: 29 December 2022 2:24 pm
