Part of Cancer staging guidance sheets
Neuroendocrine tumours of the foregut
Introduction
This is the data sheet for TNM 8th edition staging of neuroendocrine tumours of the foregut - gastric, duodenum, ampulla, proximal jejunum & pancreas.
Gastric
European neuroendocrine tumour society TNM staging summary
|
Stage Group |
T stage |
N stage |
M stage |
|---|---|---|---|
|
Stage 0 |
Tis |
N0 |
M0 |
|
Stage I |
T1 |
N0 |
M0 |
|
Stage IIa |
T2 |
N0 |
M0 |
|
Stage IIb |
T3 |
N0 |
M0 |
|
Stage IIIa |
T4 |
N0 |
M0 |
|
Stage IIIb |
Any T |
N1 |
M0 |
|
Stage IV |
Any T |
Any N |
M1 |
TNM clinical classification
T - primary tumour
| T value | Description |
|---|---|
|
TX |
Primary tumour cannot be assessed |
|
T0 |
No evidence of primary tumour |
|
Tis |
In situ tumour/dysplasia (<0.5 mm) |
|
T1 |
Tumour invades lamina propria or submucosa and ≤1 cm |
|
T2 |
Tumour invades muscularis propria or subserosa or >1 cm |
|
T3 |
Tumour penetrates serosa |
|
T4 |
Tumour invades adjacent structures |
|
|
For any T, add (m) for multiple tumours |
N - regional lymph nodes
| N value | Description |
|---|---|
|
NX |
Regional lymph nodes cannot be assessed |
|
N0 |
No regional lymph node metastasis |
|
N1 |
Regional lymph node metastasis |
M - distant metastasis
| M value | Description |
|---|---|
|
MX |
Distant metastasis cannot be assessed |
|
M0 |
No distant metastases |
|
M1 |
Distant metastasis |
Duodenum, ampulla, proximal jejunum
European neuroendocrine tumour society TNM staging summary
|
Stage Group |
T stage |
N stage |
M stage |
|---|---|---|---|
|
Stage I |
T1 |
N0 |
M0 |
|
Stage IIa |
T2 |
N0 |
M0 |
|
Stage IIb |
T3 |
N0 |
M0 |
|
Stage IIIa |
T4 |
N0 |
M0 |
|
Stage IIIb |
Any T |
N1 |
M0 |
|
Stage IV |
Any T |
Any N |
M1 |
TNM clinical classification
T - primary tumour
| T value | Description |
|---|---|
|
TX |
Primary tumour cannot be assessed |
|
T0 |
No evidence of primary tumour |
|
T1 |
Tumour invades lamina propria or submucosa and size ≤1 cma |
|
T2 |
Tumour invades muscularis propria or size >1 cm |
|
T3 |
Tumour invades pancreas or retroperitoneum |
|
T4 |
Tumour invades peritoneum or other organs |
|
|
For any T, add (m) for multiple tumours |
|
|
a - Tumour limited to ampulla of Vater for ampullary gangliocytic paraganglioma |
N - regional lymph nodes
| N value | Description |
|---|---|
|
NX |
Regional lymph nodes cannot be assessed |
|
N0 |
No regional lymph node metastasis |
|
N1 |
Regional lymph node metastasis |
M - distant metastasis
| M value | Description |
|---|---|
|
MX |
Distant metastasis cannot be assessed |
|
M0 |
No distant metastases |
|
M1 |
Distant metastasis |
Pancreas
European neuroendocrine tumour society TNM staging summary
|
Stage Group |
T stage |
N stage |
M stage |
|---|---|---|---|
|
Stage I |
T1 |
N0 |
M0 |
|
Stage IIa |
T2 |
N0 |
M0 |
|
Stage IIb |
T3 |
N0 |
M0 |
|
Stage IIIa |
T4 |
N0 |
M0 |
|
Stage IIIb |
Any T |
N1 |
M0 |
|
Stage IV |
Any T |
Any N |
M1 |
TNM classical classification
T - primary tumour
| T value | Description |
|---|---|
|
TX |
Primary tumour cannot be assessed |
|
T0 |
No evidence of primary tumour |
|
T1 |
Tumour limited to the pancreas and size <2 cm |
|
T2 |
Tumour limited to the pancreas and size 2–4 cm |
|
T3 |
Tumour limited to the pancreas and size >4 cm or invading duodenum or bile duct |
|
T4 |
Tumour invading adjacent organs (stomach, spleen, colon, adrenal gland) or the wall of large vessels (celiac axis or superior mesenteric artery) |
|
|
For any T, add (m) for multiple tumours |
N - regional lymph nodes
| N value | Description |
|---|---|
|
NX |
Regional lymph node cannot be assessed |
|
N0 |
No regional lymph node metastasis |
|
N1 |
Regional lymph node metastasis |
M - distant metastasis
| M value | Description |
|---|---|
|
MX |
Distant metastasis cannot be assessed |
|
M0 |
No distant metastases |
|
M1 |
Distant metastasis |
Last edited: 16 April 2024 1:34 pm
