Part of Cancer staging guidance sheets
Malignant melanoma of upper aerodigestive tract (ICD10 C00-06, C10-14, C30-32)
Introduction
This is the data sheet for TNM 8th edition staging of Data sheet for TNM 8th edition staging of malignant melanomas of upper aerodigestive tract (ICD10 C00-06, C10-14, C30-32).
For more detailed information regarding TNM staging, please see pages 6, 8 & 45-46 of the UICC TNM 8 book or visit the Wiley and UICC website.
Stage groupings
|
Stage Group |
T stage |
N stage |
M stage |
|---|---|---|---|
|
Stage III |
T3 |
N0 |
M0 |
|
Stage IVA |
T4a |
N0 |
M0 |
|
T3, T4a |
N1 |
M0 |
|
|
Stage IVB |
T4b |
Any N |
M0 |
|
Stage IVC |
Any T |
Any N |
M1 |
TNM clinical classification
T - primary tumour
| T value | Description |
|---|---|
|
TX |
Primary tumour cannot be assessed |
|
T0 |
No evidence of primary tumour |
|
T3 |
Tumour limited to the epithelium and/or submucosa (mucosal disease) |
|
T4a |
Tumour invades deep soft tissue, cartilage, bone, or overlying skin |
|
T4b |
Tumour invades any of the following: brain, dura, skull base, lower cranial nerves (IX, X, XI, XII), masticator space, carotid artery, prevertebral space, mediastinal structures |
Note:
Mucosal melanomas are aggressive tumours, therefore T1 and T2 are omitted as are stages I and II.
N - regional lymph nodes
| N value | Description |
|---|---|
|
NX |
Regional lymph nodes cannot be assessed |
|
N0 |
No regional lymph node metastasis |
|
N1 |
Regional lymph node metastasis |
Notes:
*Midline nodes are considered ipsilateral nodes.
**The presence of skin involvement or soft tissue invasion with deep fixation/tethering to underlying muscle or adjacent structures or clinical signs of nerve involvement is classified as clinical extranodal extension.
M - distant metastasis
| M value | Description |
|---|---|
|
M0 |
No distant metastasis |
|
M1 |
Distant Metastasis |
Note:
The MX category is considered to be inappropriate as clinical assessment of metastasis can be based on physical examination alone. (The use of MX may result in exclusion from staging.)
TNM pathological classification
The pT and pN categories correspond to the T and N categories as per above.
| pN value | Description |
|---|---|
|
pN0 |
Histological examination of a regional lymphadenectomy specimen will ordinarily include 6 or more lymph nodes. If the lymph nodes are negative, but the number ordinarily examined is not met, classify as pN0. |
pM - distant metastasis*
| pM value | Description |
|---|---|
|
pM1 |
Distant metastasis microscopically confirmed |
Note:
*pM0 and pMX are not valid categories
Last edited: 29 December 2023 10:38 am
