Part of Cancer staging guidance sheets
Major salivary glands (ICD10 C07, C08)
Introduction
This is the data sheet for TNM 8th edition staging of the major salivary glands (ICD10 C07, C08).
For more detailed information regarding TNM staging, please see pages 6, 8 & 47-50 of the UICC TNM 8 book or visit the Wiley and UICC website.
Stage groupings
|
Stage Group |
T stage |
N stage |
M stage |
|---|---|---|---|
|
Stage 0 |
Tis |
N0 |
M0 |
|
Stage I |
T1 |
N0 |
M0 |
|
Stage II |
T2 |
N0 |
M0 |
|
Stage III |
T3 |
N0 |
M0 |
|
T1, T2, T3 |
N1 |
M0 |
|
|
Stage IVA |
T1, T2, T3 |
N2 |
M0 |
|
T4a |
N0, N1, N2 |
M0 |
|
|
Stage IVB |
T4b |
Any N |
M0 |
|
Any T |
N3 |
M0 |
|
|
Stage IVC |
Any T |
Any N |
M1 |
TNM clinical classification
T - primary tumour
| T value | Description |
|---|---|
|
TX |
Primary tumour cannot be assessed |
|
T0 |
No evidence of primary tumour |
|
T1 |
Tumour 2 cm or less in greatest dimension without extraparenchymal extension* |
|
T2 |
Tumour more than 2 cm but not more than 4 cm in greatest dimension without extraparenchymal extension* |
|
T3 |
Tumour more than 4 cm and/or tumour with extraparenchymal extension* |
|
T4a |
Tumour invades skin, mandible, ear canal, and/or facial nerve |
|
T4b |
Tumour invades base of skull, and/or pterygoid plates, and/or encases carotid artery |
Note:
*Extraparenchymal extension is clinical or macroscopic evidence of invasion of soft tissues or nerve, except those listed under T4a and T4b. Microscopic evidence alone does not constitute extraparenchymal extension for classification purposes.
N - regional lymph nodes
| N value | Description |
|---|---|
|
NX |
Regional lymph nodes cannot be assessed |
|
N0 |
No regional lymph node metastasis |
|
N1 |
Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension without extranodal extension |
|
N2 |
Metastasis as described as: |
|
|
N2a - Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension without extranodal extension |
|
|
N2b - Metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension, without extranodal extension |
|
|
N2c - Metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension, without extranodal extension |
|
N3a |
Metastasis in a lymph node more than 6cm in greatest dimension without extranodal extension |
|
N3b |
Metastasis in a single or multiple lymph node with clinical extranodal extension** |
Notes:
* The presence of skin involvement or soft tissue invasion with deep fixation/tethering to underlying muscle or adjacent structures or clinical signs of nerve involvement is classified as clinical extra nodal extension.
** Midline nodes are considered ipsilateral nodes.
M - distant metastasis
| M value | Description |
|---|---|
|
M0 |
No distant metastasis |
|
M1 |
Distant Metastasis |
Note:
The MX category is considered to be inappropriate as clinical assessment of metastasis can be based on physical examination alone. (The use of MX may result in exclusion from staging.)
TNM pathological classification
pT - primary tumour
The pT categories correspond to the T categories as per above.
pN - regional lymph nodes
Histological examination of a selective neck dissection specimen will ordinarily include 10 or more lymph nodes. Histological examination of a radical or modified radical neck dissection specimen will ordinarily include 15 or more lymph nodes.
| pN value | Description |
|---|---|
|
pNX |
Regional lymph nodes cannot be assessed |
|
pN0 |
No regional lymph node metastasis |
|
pN1 |
Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension without extranodal extension |
|
pN2 |
Metastasis as described as: |
|
|
pN2a - Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension with extranodal extension or, more than 3cm but not more than 6 cm in greatest dimension without extranodal extension |
|
|
pN2b - Metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension, without extranodal extension |
|
|
pN2c - Metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension, without extranodal extension |
|
pN3a |
Metastasis in a lymph node more than 6 cm in greatest dimension without extranodal extension |
|
pN3b |
Metastasis in a lmph node more than 3cm in greatest dimension with extranodal extension or multiple ipsilateral, or any contralateral, or bilateral node(s) with extranodal extension |
pM - distant metastasis*
| pM value | Description |
|---|---|
|
pM1 |
Distant metastasis microscopically confirmed |
Note:
*pM0 and pMX are not valid categories
Last edited: 4 January 2024 9:38 am
