Part of Cancer staging guidance sheets
Neuroendocrine tumours of the midgut and hindgut
Introduction
This is the data sheet for TNM 8th edition staging of neuroendocrine tumours of the midgut and hindgut - lower jejunum and ileum, appendix and colon & rectum
Lower jejunum and ileum
European neuroendocrine tumour society TNM staging summary
|
Stage Group |
T stage |
N stage |
M stage |
|---|---|---|---|
|
Stage I |
T1 |
N0 |
M0 |
|
Stage IIA |
T2 |
N0 |
M0 |
|
Stage IIB |
T3 |
N0 |
M0 |
|
Stage IIIA |
T4 |
N0 |
M0 |
|
Stage IIIB |
Any T |
N1 |
M0 |
|
Stage IV |
Any T |
Any N |
M1 |
TNM clinical classification
T - primary tumour
| T value | Description |
|---|---|
|
TX |
Primary tumour cannot be assessed |
|
T0 |
No evidence of primary tumour |
|
T1 |
Tumour invades mucosa or submucosa and size ≤1 cm |
|
T2 |
Tumour invades muscularis propria or size >1 cm |
|
T3 |
Tumour invades subserosa |
|
T4 |
Tumour invades peritoneum/other organs |
|
|
For any T add (m) for multiple tumours |
|
|
a - Tumour limited to ampulla of Vater for ampullary gangliocytic paraganglioma |
N - regional lymph nodes
| N value | Description |
|---|---|
|
NX |
Regional lymph nodes cannot be assessed |
|
N0 |
No regional lymph node metastasis |
|
N1 |
Regional lymph node metastasis |
M - distant metastasis
| M value | Description |
|---|---|
|
MX |
Distant metastasis cannot be assessed |
|
M0 |
No distant metastases |
|
M1 |
Distant metastasis |
Appendix
European neuroendocrine tumour society TNM staging summary
|
Stage Group |
T stage |
N stage |
M stage |
|---|---|---|---|
|
Stage I |
T1 |
N0 |
M0 |
|
Stage IIA |
T2 |
N0 |
M0 |
|
Stage IIB |
T3 |
N0 |
M0 |
|
Stage IIIA |
T4 |
N0 |
M0 |
|
Stage IIIB |
Any T |
N1 |
M0 |
|
Stage IV |
Any T |
Any N |
M1 |
TNM clinical classification
T - primary tumour
| T value | Description |
|---|---|
|
TX |
Primary tumour cannot be assessed |
|
T0 |
No evidence of primary tumour |
|
T1 |
Tumour ≤1 cm invading submucosa and muscularis propria |
|
T2 |
Tumour ≤2 cm invading submucosa, muscularis propria and/or minimally (up to 3 mm) invading subserosa/mesoappendix |
|
T3 |
Tumour >2 cm and/or extensive (more than 3 mm) invasion of subserosa/mesoappendix |
|
T4 |
Tumour invades peritoneum/other organs |
|
|
For any T add (m) for multiple tumours |
|
|
a - Tumour limited to ampulla of Vater for ampullary gangliocytic paraganglioma |
N - regional lymph nodes
| N value | Description |
|---|---|
|
NX |
Regional lymph nodes cannot be assessed |
|
N0 |
No regional lymph node metastasis |
|
N1 |
Regional lymph node metastasis |
M - distant metastasis
| M value | Description |
|---|---|
|
MX |
Distant metastasis cannot be assessed |
|
M0 |
No distant metastases |
|
M1 |
Distant metastasis |
Colon and rectum
European neuroendocrine tumour society TNM staging summary
|
Stage Group |
T stage |
N stage |
M stage |
|---|---|---|---|
|
Stage IA |
T1a |
N0 |
M0 |
|
Stage IB |
T1b |
N0 |
M0 |
|
Stage IIA |
T2 |
N0 |
M0 |
|
Stage IIB |
T3 |
N0 |
M0 |
|
Stage IIIA |
T4 |
N0 |
M0 |
|
Stage IIIB |
Any T |
N1 |
M0 |
|
Stage IV |
Any T |
Any N |
M1 |
TNM classical classification
T - primary tumour
| T value | Description |
|---|---|
|
TX |
Primary tumour cannot be assessed |
|
T0 |
No evidence of primary tumour |
|
T1 |
Tumour invades mucosa or submucosa T1a - size <1 cm T1b - size 1–2 cm |
|
T2 |
Tumour invades muscularis propria or size >2 cm |
|
T3 |
Tumour invades subserosa/pericolic/perirectal fat |
|
T4 |
Tumour directly invades other organs/structures and/or perforates visceral peritoneum |
|
|
For any T add (m) for multiple tumours |
N - regional lymph nodes
| N value | Description |
|---|---|
|
NX |
Regional lymph node status cannot be assessed |
|
N0 |
No regional lymph node metastasis |
|
N1 |
Regional lymph node metastasis |
M - distant metastasis
| M value | Description |
|---|---|
|
MX |
Distant metastasis cannot be assessed |
|
M0 |
No distant metastases |
|
M1 |
Distant metastasis |
Last edited: 16 April 2024 1:33 pm
